PHE or Phe may refer to:


== Science and technology ==
Protocol header encrypt or BitTorrent protocol encryption
Phenylalanine (symbol: Phe), an amino acid
Phoenix (constellation) (IAU abbreviation: Phe)


== Organisations ==
Paramount Home Entertainment, the home video distribution arm of Paramount Pictures
Public Health England, an executive agency of the Department of Health in the UK
Physical and Health Education Canada (PHE Canada), a Canadian health organization; See Canada Fitness Award Program


== Other uses ==
Population, health, and the environment, an approach to development that integrates health or family planning with conservation efforts
Port Hedland International Airport (IATA code), Australia